Nasal monkeypox virus infection successfully treated with cidofovir in a patient newly diagnosed with HIV

Laura Labate; Giorgia Brucci; Giulia Ciccarese; Bianca Bruzzone; Valentina Ricucci; Federica Stefanelli; Emanuele Delfino; Lucia Taramasso; Matteo Bassetti; Antonio Di Biagio

doi:10.1177/09564624221141152

Nasal monkeypox virus infection successfully treated with cidofovir in a patient newly diagnosed with HIV

Int J STD AIDS. 2023 Mar;34(3):208-210. doi: 10.1177/09564624221141152. Epub 2022 Dec 15.

Authors

Affiliations

¹ Dipartimento di Scienze Della Salute (DISSAL), 9246Università degli Studi di Genova, Genoa, Italy.
² Dermatology Unit, 9246San Martino Hospital, Genoa, Italy.
³ Hygiene Unit, 9246Ospedale Policlinico San Martino - IRCCS, Genoa, Italy.
⁴ Dipartimento di Scienze della Salute, 9246IRCCS Ospedale Policlinico San Martino, Genova, Italy.

PMID: 36520997
DOI: 10.1177/09564624221141152

Abstract

Monkeypox (MPXV) usually causes a mild and self-limited infection. To date there are no data about cidofovir for the treatment for MPXV in humans. We report a case of a 25 years-old Brazilian man with a concurrent diagnosis of acute HIV (human immunodeficiency virus) infection, primary syphilis and MPXV infection with a nasal lesion successfully treated with intravenous cidofovir.

Keywords: HIV; Monkeypox-virus; cidofovir; syphilis.

Publication types

Case Reports

MeSH terms

Adult
Brazil
Cidofovir / therapeutic use
Humans
Male
Monkeypox virus*
Mpox (monkeypox)* / diagnosis
Mpox (monkeypox)* / pathology

Substances

Cidofovir