Familial Adenomatous Polyposis: Case Report and Literature Review

Cureus. 2022 Nov 17;14(11):e31609. doi: 10.7759/cureus.31609. eCollection 2022 Nov.

Abstract

Familial adenomatous polyposis (FAP) is an autosomal inheritance disease characterized by 100 or more adenomatous polyps in the colon and rectum with a high risk of developing colorectal carcinoma (CRC). The management of this disease is based on early screening and timely follow up, with subsequent planning of risk-reducing or therapeutic surgeries. We present a case of a patient with a strong family history of FAP with a "de novo" diagnosis of CRC. Furthermore, a literature discussion of current and future perspectives of treatment is performed.

Keywords: colombia; colorectal cancer; familial adenomatous polyposis; family research; genetic syndromes.

Publication types

  • Case Reports