Generation of new transgenic SMARCA4-deficient mouse models results in neuromuscular weakness and paralysis of limbs

Sina Neyazi; Lea Altendorf; Dora Schwetje; Carolin Göbel; Melanie Schoof; Dörthe Holdhof; Ulrich Schüller

doi:10.1111/bpa.13146

Generation of new transgenic SMARCA4-deficient mouse models results in neuromuscular weakness and paralysis of limbs

Brain Pathol. 2023 May;33(3):e13146. doi: 10.1111/bpa.13146. Epub 2022 Dec 29.

Authors

Sina Neyazi^{1

2

3}, Lea Altendorf^{1

2}, Dora Schwetje^{1

2

4}, Carolin Göbel^{1

2}, Melanie Schoof^{1

2}, Dörthe Holdhof^{1

2}, Ulrich Schüller^{1

2

5}

Affiliations

¹ Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
² Research Institute Children's Cancer Center Hamburg, Hamburg, Germany.
³ Department of Pediatric Oncology, Dana-Farber Cancer Institute Boston, Massachusetts, USA.
⁴ Research Group Anatomy, School of Medicine and Health Studies, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
⁵ Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

No abstract available

Keywords: SMARCA4; mouse model; rhabdoid tumors.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biomarkers, Tumor*
Central Nervous System Diseases / genetics
Central Nervous System Diseases / metabolism
Mice
Muscular Diseases / genetics
Muscular Diseases / metabolism
Paralysis*

Substances

Biomarkers, Tumor
Smarca4 protein, mouse