Cytomegalovirus lymphadenitis mimicking a relapsed diffuse large B-cell lymphoma

Matthieu Delaye; Laure Ricard; Lucas Maisonobe; Suzanne Chartier; Paul Coppo

doi:10.1002/ccr3.6611

Cytomegalovirus lymphadenitis mimicking a relapsed diffuse large B-cell lymphoma

Clin Case Rep. 2022 Dec 26;10(12):e6611. doi: 10.1002/ccr3.6611. eCollection 2022 Dec.

Authors

Matthieu Delaye¹, Laure Ricard¹, Lucas Maisonobe², Suzanne Chartier³, Paul Coppo^{1

4

5}

Affiliations

¹ Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, AP-HP Sorbonne University Paris France.
² Infectious Diseases Department, Hôpital Saint-Antoine Groupe Hospitalier Sorbonne Université, APHP Paris France.
³ Department of Pathology, AP-HP Hôpital Saint Antoine Paris France.
⁴ Reference Center for Thrombotic Microangiopathies (CNR-MAT), AP-HP Paris France.
⁵ INSERM UMRS1138 Centre de Recherche des Cordeliers Paris France.

Abstract

Cytomegalovirus (CMV) reactivation is frequent after autologous stem cell transplantation (ASCT), but generalized CMV lymphadenitis is rare. We report a CMV lymphadenitis after an ASCT mimicking a relapse of a diffuse large B-cell lymphoma. After histopathological documentation, CMV lymphadenitis should be treated to avoid systemic progression.

Keywords: autologous stem cell transplantation; cytomegalovirus; lymphadenitis; lymphoma.

Publication types

Case Reports