An Omniphobic Spray Coating Created from Hierarchical Structures Prevents the Contamination of High-Touch Surfaces with Pathogens

Small. 2023 Mar;19(12):e2205761. doi: 10.1002/smll.202205761. Epub 2023 Jan 1.

Abstract

Engineered surfaces that repel pathogens are of great interest due to their role in mitigating the spread of infectious diseases. A robust, universal, and scalable omniphobic spray coating with excellent repellency against water, oil, and pathogens is presented. The coating is substrate-independent and relies on hierarchically structured polydimethylsiloxane (PDMS) microparticles, decorated with gold nanoparticles (AuNPs). Wettability studies reveal the relationship between surface texturing of micro- and/or nano-hierarchical structures and the omniphobicity of the coating. Studies of pathogen transfer with bacteria and viruses reveal that an uncoated contaminated glove transfers pathogens to >50 subsequent surfaces, while a coated glove picks up 104 (over 99.99%) less pathogens upon first contact and transfers zero pathogens after the second touch. The developed coating also provides excellent stability under harsh conditions. The remarkable anti-pathogen properties of this surface combined with its ease of implementation, substantiate its use for the prevention of surface-mediated transmission of pathogens.

Keywords: healthcare-acquired infections; hierarchical structures; omniphobic surfaces; pathogen repellent; spray-coatings.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gold*
  • Hydrophobic and Hydrophilic Interactions
  • Metal Nanoparticles*
  • Surface Properties
  • Touch

Substances

  • Gold