Stereotactic Body Radiotherapy for a Rare Case of Sinonasal Metastasis Arising from Renal Cell Cancer

In Vivo. 2023 Jan-Feb;37(1):490-492. doi: 10.21873/invivo.13104.

Abstract

Background/aim: Sinonasal metastases arising from renal cell cancer are rare and usually managed with surgery. Few studies describe the use of radiotherapy in this specific setting, while the use of stereotactic body radiotherapy (SBRT) has been rarely reported as well.

Case report: We present the case of a solitary left sinonasal metastasis in a 65-year-old man with clear cell renal cancer who also received bilateral nephrectomy and subsequent kidney transplantation. The patient received subtotal surgery and subsequently he was candidate to SBRT to avoid systemic treatment, due to renal comorbidities.

Conclusion: The patient was treated with SBRT for a total dose of 35 Gy in 5 fractions and after 24 months of follow-up there is no evidence of local relapse. No major side-effects were reported. Our experience supports SBRT as a safe and feasible treatment option in the case of sinonasal metastases from RCC.

Keywords: Renal cell cancer; solitary metastasis; stereotactic body radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Renal Cell* / radiotherapy
  • Carcinoma, Renal Cell* / surgery
  • Follow-Up Studies
  • Humans
  • Kidney Neoplasms* / pathology
  • Male
  • Neoplasm Recurrence, Local / surgery
  • Radiosurgery*