DRC3 is an assembly adapter of the nexin-dynein regulatory complex functional components during spermatogenesis in humans and mice

Shushu Zhou; Shimin Yuan; Jintao Zhang; Lanlan Meng; Xin Zhang; Siyu Liu; Guangxiu Lu; Ge Lin; Mingxi Liu; Yue-Qiu Tan

doi:10.1038/s41392-022-01293-4

DRC3 is an assembly adapter of the nexin-dynein regulatory complex functional components during spermatogenesis in humans and mice

Signal Transduct Target Ther. 2023 Jan 10;8(1):26. doi: 10.1038/s41392-022-01293-4.

Authors

Shushu Zhou^#^{1

2}, Shimin Yuan^#³, Jintao Zhang^#¹, Lanlan Meng^{3

4}, Xin Zhang¹, Siyu Liu¹, Guangxiu Lu^{3

4

5}, Ge Lin^{3

4

5}, Mingxi Liu⁶, Yue-Qiu Tan^{7

8

9}

Affiliations

¹ State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
² Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
³ Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410008, China.
⁴ Institute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410008, China.
⁵ Hunan International Scientific and Technological Cooperation base of Development and carcinogenesis, Changsha, 410008, China.
⁶ State Key Laboratory of Reproductive Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Nanjing, 211166, China. mingxi.liu@njmu.edu.cn.
⁷ Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410008, China. tanyueqiu@csu.edu.cn.
⁸ Institute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410008, China. tanyueqiu@csu.edu.cn.
⁹ Hunan International Scientific and Technological Cooperation base of Development and carcinogenesis, Changsha, 410008, China. tanyueqiu@csu.edu.cn.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Axoneme / metabolism
Cytoskeleton
Dyneins* / metabolism
Humans
Male
Mice
Microtubule-Associated Proteins*
Spermatogenesis / genetics

Substances

Dyneins
Microtubule-Associated Proteins