Cross-sectional and longitudinal study of the relationship between phase angle and physical function in older adults

Geriatr Gerontol Int. 2023 Feb;23(2):141-147. doi: 10.1111/ggi.14532. Epub 2023 Jan 19.

Abstract

Aim: Although the validity of the assessment in older adults has been supported by several studies, cross-sectional and longitudinal relationships between phase angle (PhA) and physical function by sex have not been clarified. This study aimed to examine (i) cross-sectional relationships and (ii) longitudinal relationships between PhA and physical function in older adults.

Methods: A total of 816 and 445 community-dwelling older adults were included in cross-sectional and longitudinal analyses, respectively. We evaluated their physical function using grip strength, 5-repetition sit-to-stand test (5-STS), 5-meter habitual walk, Timed Up and Go test (TUG), single-leg balance with eyes open, and sit-and-reach test. A multifrequency bioelectrical impedance analyzer was used to determine the PhA at 50 kHz as well as the participants' body composition.

Results: In the cross-sectional analysis, a higher PhA was significantly associated with higher grip strength, sit-and-reach, single-leg balance with eyes open, 5-STS and lower TUG in women, as well as higher grip strength, single-leg balance with eyes open, lower 5-STS and TUG in men, adjusting for age, body mass index and muscle mass. In the longitudinal analysis, there was a significant interaction between PhA and year in the TUG test (B = -0.08; 95% CI, -0.136 to -0.025; P = 0.005) in men. There was no significant interaction between the PhA value and year for the other physical functions.

Conclusions: The PhA is a useful indicator for assessing physical function in both older men and women. Furthermore, the PhA may be able to predict mobility limitation in older men. Geriatr Gerontol Int 2023; 23: 141-147.

Keywords: Kasama study; bioelectrical impedance analysis; mixed-effects model; mobility limitation.

MeSH terms

  • Aged
  • Female
  • Humans
  • Independent Living*
  • Longitudinal Studies
  • Male
  • Postural Balance* / physiology
  • Time and Motion Studies
  • Walking / physiology