Biological responses to terahertz radiation with different power density in primary hippocampal neurons

Li Zhao; Ruhan Yi; Sun Liu; Yunliang Chi; Shengzhi Tan; Ji Dong; Hui Wang; Jing Zhang; Haoyu Wang; Xinping Xu; Binwei Yao; Bo Wang; Ruiyun Peng

doi:10.1371/journal.pone.0267064

Biological responses to terahertz radiation with different power density in primary hippocampal neurons

PLoS One. 2023 Jan 20;18(1):e0267064. doi: 10.1371/journal.pone.0267064. eCollection 2023.

Authors

Li Zhao¹, Ruhan Yi¹, Sun Liu¹, Yunliang Chi¹, Shengzhi Tan¹, Ji Dong¹, Hui Wang¹, Jing Zhang¹, Haoyu Wang¹, Xinping Xu¹, Binwei Yao¹, Bo Wang², Ruiyun Peng¹

Affiliations

¹ Beijing Institute of Radiation Medicine, Beijing, PR China.
² Central Laboratory, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, PR China.

Abstract

Terahertz (THz) radiation is a valuable imaging and sensing tool which is widely used in industry and medicine. However, it biological effects including genotoxicity and cytotoxicity are lacking of research, particularly on the nervous system. In this study, we investigated how terahertz radiation with 10mW (0.12 THz) and 50 mW (0.157 THz) would affect the morphology, cell growth and function of rat hippocampal neurons in vitro.

Copyright: © 2023 Zhao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
DNA Damage
Diagnostic Imaging*
Hippocampus
Neurons
Rats
Terahertz Radiation*

Grants and funding

This work was supported by the National Defense Technology Innovation Special Zone. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. No author received a salary from any of our funders.