Barrier behaviour of partially N-acetylated chitosan layers in aqueous media

Int J Biol Macromol. 2023 Mar 31:232:123336. doi: 10.1016/j.ijbiomac.2023.123336. Epub 2023 Jan 26.

Abstract

Chitosan coatings of 353 ± 12 nm thickness were prepared on glass and zinc substrates by dip-coating method to study their barrier-behaviour. The coatings were chemically modified to increase their degree of acetylation (DA) from ca. 44 % up to ca. 98 % resulting a quasi-chitin coating. The effect of the acetylation reaction was studied by infrared spectroscopy, and the structural changes of the native and acetylated coatings were investigated by UV-Vis spectrophotometry and X-ray diffraction. The surface properties of the coated samples were characterized by wettability measurements - advancing water contact angle decreased from ca. 80° (native) to ca. 43° (fully acetylated) - and microscopic (SEM, AFM) studies. The barrier behaviour of the chitosan layer depending on the DA was evaluated by electrochemical impedance spectroscopy studies and with a special mesoporous silica - chitosan bilayer system by measuring the amount of dye (Rhodamine 6G) accumulated in the silica through the chitosan coating during an impregnation step. These methods showed significant decrease in the barrier-effect of the coatings with increasing DA (accumulation of approximately six times more dye and a reduction of charge transfer resistance by an order of magnitude), due to the structural and ionization changes in the coatings.

Keywords: Acetylation; Barrier-effect; Chitosan coating; Electrochemical impedance spectroscopy; Wettability.

MeSH terms

  • Chitin / chemistry
  • Chitosan* / chemistry
  • Coated Materials, Biocompatible / chemistry
  • Silicon Dioxide
  • Surface Properties
  • Water

Substances

  • Chitosan
  • Chitin
  • Water
  • Silicon Dioxide
  • Coated Materials, Biocompatible