Pancreatic neuroendocrine tumors: tailoring imaging to specific clinical scenarios

Abdom Radiol (NY). 2023 May;48(5):1843-1853. doi: 10.1007/s00261-022-03737-5. Epub 2023 Feb 4.

Abstract

The clinical and imaging presentation of pancreatic neuroendocrine tumors (PanNETs) is variable and depends on tumor grade, stage, and functional status. This degree of variability combined with a multitude of treatment options and imaging modalities results in complexity when choosing the most appropriate imaging studies across various clinical scenarios. While various guidelines exist in the management and evaluation of PanNETs, there is an overall lack of consensus and detail regarding optimal imaging guidelines and protocols. This manuscript aims to fill gaps where current guidelines may lack specificity regarding the choice of the most appropriate imaging study in the diagnosis, treatment planning, monitoring, and surveillance of PanNETs under various clinical scenarios.

Keywords: CT; Imaging; MRI; Pancreatic neuroendocrine neoplasm; Somatostatin receptor PET.

Publication types

  • Review

MeSH terms

  • Diagnostic Imaging
  • Humans
  • Neuroendocrine Tumors* / diagnostic imaging
  • Neuroendocrine Tumors* / pathology
  • Pancreatic Neoplasms* / diagnostic imaging
  • Pancreatic Neoplasms* / pathology