Treatment of massive haematuria with aluminous salts

Br J Urol. 1987 Sep;60(3):223-6. doi: 10.1111/j.1464-410x.1987.tb05487.x.

Abstract

Fifteen patients with massive vesical haematuria were treated with a 1% aluminium potassium sulphate solution in sterile distilled water, using continuous intravesical lavage with a double channel catheter. The haematuria was caused by vesical tumours in 13 patients, radiation cystitis in one and transurethral resection in one. Immediate side effects were few and none were noted in the long term, as judged by randomised biopsies from vesical mucosa. A complete response was noted in 66% of the patients, partial response in 15% and failure in 20%. This treatment is recommended for intractable bleeding from radiation cystitis and bladder tumours.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alum Compounds / therapeutic use*
  • Aluminum / therapeutic use*
  • Cystitis / complications
  • Cystitis / etiology
  • Female
  • Hematuria / drug therapy*
  • Hematuria / etiology
  • Hematuria / pathology
  • Humans
  • Male
  • Middle Aged
  • Radiotherapy / adverse effects
  • Therapeutic Irrigation
  • Urinary Bladder / pathology
  • Urinary Bladder Neoplasms / complications

Substances

  • Alum Compounds
  • Aluminum