Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems

Pharmaceutics. 2023 Feb 20;15(2):702. doi: 10.3390/pharmaceutics15020702.

Abstract

Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids "Solutions for Your Success" have received a lot of interest from scientists due to a myriad of applications in the pharmaceutical industry for drug delivery systems as well as targeting different diseases. Solubility is a critical physicochemical property that determines the drug's fate at the target site. Many promising drug candidates fail in various phases of drug research due to poor solubility. In this context, ionic liquids are regarded as effective drug delivery systems for poorly soluble medicines. ILs are also able to combine different anions/cations with other cations/anions to produce salts that satisfy the concept behind the ILs. The important characteristics of ionic liquids are the modularity of their physicochemical properties depending on the application. The review highlights the recent advancement and further applications of ionic liquids to deliver drugs in the pharmaceutical and biomedical fields.

Keywords: biological macromolecules; biomedical applications; drug delivery systems; ionic liquids; water solubility.

Publication types

  • Review

Grants and funding

This research received no external funding.