Treatment intensification might not improve survival in high-grade B-cell lymphoma with a concurrent MYC and BCL2 and/or BCL6 rearrangement: A retrospective, multicenter, pooled analysis

Hematol Oncol. 2023 Oct;41(4):776-780. doi: 10.1002/hon.3130. Epub 2023 Mar 21.
No abstract available

Keywords: double-hit; induction treatment; lymphoma; overall survival; triple-hit.

Publication types

  • Multicenter Study
  • Letter

MeSH terms

  • Gene Rearrangement
  • Humans
  • Lymphoma, Large B-Cell, Diffuse* / pathology
  • Proto-Oncogene Proteins c-bcl-2 / genetics
  • Proto-Oncogene Proteins c-bcl-6 / genetics
  • Proto-Oncogene Proteins c-myc / genetics
  • Retrospective Studies

Substances

  • Proto-Oncogene Proteins c-bcl-2
  • Proto-Oncogene Proteins c-myc
  • Proto-Oncogene Proteins c-bcl-6
  • BCL6 protein, human
  • BCL2 protein, human