Contour device implantation versus coil embolization for treatment of narrow neck intracranial aneurysms

Sci Rep. 2023 Mar 25;13(1):4904. doi: 10.1038/s41598-023-31877-1.

Abstract

The novel Contour device is an intrasaccular flow disruption device designed for treatment of intracranial wide-neck bifurcation aneurysms. Outside its original purpose, Contour implantation can be used to treat aneurysms with a higher dome-to-neck ratio which would be suitable for conventional unassisted coil embolization. We compared both techniques in a retrospective single-center analysis. A total of 42 aneurysms from 42 patients with a dome-to-neck ratio of 1.6 or higher were included in this study. Data on technical success, implantation times, radiation dosages, procedural complications, reinterventions and recurrences were gathered and compared. Technical success was achieved in all cases with both techniques. Aneurysm embolization was achieved significantly faster in the Contour group compared to coiling (Overall p = 0.0002; r = 0.580; acute setting: p = 0.005, r = 0.531; elective setting: p = 0.002, r = 0.607). Significantly less radiation dosage was applied in the Contour group (Overall p = 0.002; r = 0.478; acute group p = 0.006; r = 0.552; elective group p = 0.045; r = 0.397). The number of complications was higher in the coiling group compared to the Contour group (Coiling 7/21 (33,3%); Contour 3/21 (14.3%). There was a higher rate of reinterventions in the coiling group (7.6% vs 21.4%). Outside its original intention, the Contour device seems to be a safe and fast alternative to coil embolization for the treatment of narrow-neck-aneurysms.

MeSH terms

  • Blood Vessel Prosthesis
  • Cerebral Angiography
  • Embolization, Therapeutic* / methods
  • Endovascular Procedures*
  • Humans
  • Intracranial Aneurysm* / complications
  • Intracranial Aneurysm* / therapy
  • Musculoskeletal Abnormalities*
  • Retrospective Studies
  • Stents
  • Treatment Outcome