Editorial: Restoring endoplasmic reticulum proteostasis to treat neurological disorders

Danilo B Medinas; Najla Arshad; Sonam Parakh; Sayuri Miyamoto; Vanessa Olzon Zambelli

doi:10.3389/fphar.2023.1176805

Editorial: Restoring endoplasmic reticulum proteostasis to treat neurological disorders

Front Pharmacol. 2023 Mar 9:14:1176805. doi: 10.3389/fphar.2023.1176805. eCollection 2023.

Authors

Danilo B Medinas^{1

2

3

4}, Najla Arshad⁵, Sonam Parakh⁶, Sayuri Miyamoto¹, Vanessa Olzon Zambelli⁷

Affiliations

¹ Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP, Brazil.
² Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
³ Center for Geroscience, Brain Health, and Metabolism, Santiago, Chile.
⁴ Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.
⁵ Department of Immunobiology, Yale University School of Medicine, New Haven, CT, United States.
⁶ Department of Biomedical Sciences, Centre for MND Research, Faculty of Medicine, Health, and Human Sciences, Macquarie University, Sydney, NSW, Australia.
⁷ Laboratory of Pain and Signaling, Butantan Institute, Sāo Paulo, SP, Brazil.

No abstract available

Keywords: drug discovery; endoplasmic reticulum; ischemia-reperfusion injury; neurological disorders; proteostasis; small molecules; spinal cord injury; unfolded protein response.

Publication types

Editorial

Grants and funding

This work was funded by FONDECYT 1191538 (DBM), grant 2021/06287-6 (DBM), grant 2013/07937-8 (DBM and SM), grant 21/14831-8 (VOZ), São Paulo Research Foundation (FAPESP); MND research Australia (MNDRA) and The Dementia Australia Research Foundation (DARF) (SP); Neurodegenerative Disease Research Inc. (NDR) (SM); and National Council for Scientific and Technological Development (CNPQ) grant 429221/2018-5 (VOZ).