Quality of Life in Patients with Pancreatic Cancer-A Literature Review

Int J Environ Res Public Health. 2023 Mar 10;20(6):4895. doi: 10.3390/ijerph20064895.

Abstract

Pancreatic cancer is the malignant disease with the highest mortality rate, and it ranks third in the world after lung and colon cancer. Identified factors that increase the risk of developing pancreatic cancer include chronic pancreatitis, radiation therapy to the pancreatic area due to another cancer, diabetes mellitus, obesity, smoking, and age. The objective of this study was to present the current state of knowledge on the quality of life of patients diagnosed with pancreatic cancer, factors that determine QoL, and ways of coping with the disease. The low curability and low survival rates of pancreatic cancer significantly affect the quality of life of patients, often in the form of significant deterioration, especially in terms of mental changes, cognitive functions, and coping with the disease. Cognitive decline with comorbid depression is also typical for patients with this type of cancer. Research has shown that the health-related quality of life of patients with pancreatic cancer is low, so further research is needed to improve the situation in this area.

Keywords: literature review; mental adjustment to disease; pain management; pancreatic cancer; quality of life.

Publication types

  • Review

MeSH terms

  • Comorbidity
  • Diabetes Mellitus*
  • Humans
  • Pancreatic Neoplasms* / epidemiology
  • Pancreatitis, Chronic* / psychology
  • Quality of Life

Grants and funding

This research received no external funding.