High-prevalence rates and increased morbidity suggest that loneliness is a major public health concern warranting novel health-care strategies and interventions promoting social connectedness. Social prescribing (SP) constitutes such strategy and is, despite scarce evidence, increasingly promoted. Focusing primarily on building and maintaining social support, SP appears especially relevant in connection to community-based physical activity. In this review, we introduce and discuss the adaptation of SP in the context of the Danish healthcare system and provide examples of current research initiatives.