Objectives: This study aimed to summarize the state of current literature and evaluate evidence for timing, methods, and effects of early intervention in patients after free flap reconstruction.
Methods: A comprehensive search was conducted in nine databases. The methodological quality of literature was assessed according to the JBI Critical Appraisal Tools.
Results: Eight studies were finally included. Most studies started the intervention within 1 to 2 weeks after surgery with multiple swallowing training measures. The results of meta-analysis showed that swallowing intervention could improve swallowing function (SMD = -1.03, 95%CI [-1.37, -0.69], Z = 5.95, p < 0.01) and the quality of life (SMD = 1.52, 95%CI [0.97, 2.07], Z = 5.43, p < 0.01).
Conclusion: Early swallowing intervention can improve patients' swallowing function and short-term quality of life. We can only summarize the basic consensus of the studies on early swallowing intervention, and rigorous trials are needed in the future.
Keywords: deglutition disorders; free flap reconstruction; mouth neoplasms; swallowing intervention; systematic review.
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