Similarities and differences between the cough suppression test and the cough challenge test

Ther Adv Respir Dis. 2023 Jan-Dec:17:17534666231162246. doi: 10.1177/17534666231162246.

Abstract

In recent years, a new test method namely the cough suppression test has been proposed to measure cough suppression in patients with chronic cough. The cough suppression test is a modified test based on capsaicin tussive challenge. There are similarities and differences between it and the more established cough challenge test in detection method, purpose and clinical significance. In this article, we will introduce and compare the concepts, application and methodology of the cough suppression test and the cough challenge test, summarize this research progress and problems of the two methods, and predict the possible role of both in the further study of chronic cough.

Keywords: cough challenge test; cough hypersensitivity syndrome; cough sensitivity; cough suppression test.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Capsaicin*
  • Chronic Disease
  • Cough* / diagnosis
  • Cough* / etiology
  • Humans

Substances

  • Capsaicin