Small RNAs: Efficient and miraculous effectors that play key roles in plant-microbe interactions

Mol Plant Pathol. 2023 Aug;24(8):999-1013. doi: 10.1111/mpp.13329. Epub 2023 Apr 7.

Abstract

Plants' response to pathogens is highly complex and involves changes at different levels, such as activation or repression of a vast array of genes. Recently, many studies have demonstrated that many RNAs, especially small RNAs (sRNAs), are involved in genetic expression and reprogramming affecting plant-pathogen interactions. The sRNAs, including short interfering RNAs and microRNAs, are noncoding RNA with 18-30 nucleotides, and are recognized as key genetic and epigenetic regulators. In this review, we summarize the new findings about defence-related sRNAs in the response to pathogens and our current understanding of their effects on plant-pathogen interactions. The main content of this review article includes the roles of sRNAs in plant-pathogen interactions, cross-kingdom sRNA trafficking between host and pathogen, and the application of RNA-based fungicides for plant disease control.

Keywords: RNA interference (RNAi); cross-kingdom trafficking; plant immunity; plant-pathogen interaction; small RNA.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Host-Pathogen Interactions* / genetics
  • MicroRNAs* / genetics
  • MicroRNAs* / metabolism
  • Plants / genetics
  • Plants / metabolism
  • RNA Interference
  • RNA, Small Interfering / metabolism

Substances

  • RNA, Small Interfering
  • MicroRNAs