Migraine and the Gender Divide

Aimen Vanood; India C Rangel; Amaal J Starling

doi:10.1016/j.ncl.2023.01.002

Migraine and the Gender Divide

Neurol Clin. 2023 May;41(2):231-247. doi: 10.1016/j.ncl.2023.01.002.

Authors

Aimen Vanood¹, India C Rangel², Amaal J Starling³

Affiliations

¹ Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA.
² Mayo Clinic Alix School of Medicine, Scottsdale, AZ, USA.
³ Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA. Electronic address: starling.amaal@mayo.edu.

PMID: 37030955
DOI: 10.1016/j.ncl.2023.01.002

Abstract

Migraine is a global neurologic disease that is highly prevalent, especially in women. Studies have observed a predisposition for the development of migraine in women, although the mechanisms involved have yet to be fully elucidated. This review aimed to summarize the recent evidence regarding the epidemiology, pathophysiology, and treatment of migraine and highlight key sex differences. We also identify gaps in care for both women and men living with migraine and discuss the presence of migraine-related stigma and how this may impact the efficacy of clinical care.

Keywords: Female; Headache; Migraine; Pain.

Publication types

Review

MeSH terms

Female
Humans
Male
Migraine Disorders* / diagnosis
Migraine Disorders* / epidemiology
Migraine Disorders* / therapy
Sex Factors*