Hospital EEG Capability and Associations With Interhospital Transfer in Status Epilepticus

Catherine G Suen; Andrew J Wood; James F Burke; John P Betjemann; Elan L Guterman

doi:10.1212/CPJ.0000000000200143

Hospital EEG Capability and Associations With Interhospital Transfer in Status Epilepticus

Neurol Clin Pract. 2023 Apr;13(2):e200143. doi: 10.1212/CPJ.0000000000200143. Epub 2023 Mar 16.

Authors

Catherine G Suen¹, Andrew J Wood¹, James F Burke¹, John P Betjemann¹, Elan L Guterman¹

Affiliation

¹ Department of Neurology (C.G.S., A.J.W., E.L.G.), University of California San Francisco; Department of Neurology (J.F.B.), Ohio State Wexner Medical Center, Columbus; Department of Neurology (J.P.B.), Kaiser Permanente Northern California, San Francisco; Philip R. Lee Institute for Health Policy Studies (E.L.G.), University of California, San Francisco.

Abstract

Background and objectives: EEG is widely recommended for status epilepticus (SE) management. However, EEG access and use across the United States is poorly characterized. We aimed to evaluate changes in inpatient EEG access over time and whether availability of EEG is associated with interhospital transfers for patients hospitalized with SE.

Methods: We performed a cross-sectional study using data available in the National Inpatient Sample data set from 2012 to 2018. We identified hospitals that used continuous or routine EEG during at least 1 seizure-related hospitalization in a given year using ICD-9 and ICD-10 procedure codes and defined these hospitals as EEG capable. We examined annual change in the proportion of hospitals that were EEG capable during the study period, compared characteristics of hospitals that were EEG capable with those that were not, and fit multivariable logistic regression models to determine whether hospital EEG capability was associated with likelihood of interhospital transfer.

Results: Among 4,550 hospitals in 2018, 1,241 (27.3%) were EEG capable. Of these, 1,188 hospitals (95.7%) were in urban settings. From 2012 to 2018, the proportion of hospitals that were EEG capable increased in urban settings (30.5%-41.1%, Mann-Kendall [M-K] test p < 0.001) and decreased in rural settings (4.0%-3.2%, M-K p = 0.026). Among 130,580 patients hospitalized with SE, 80,725 (61.8%) presented directly to an EEG-capable hospital. However, EEG use during hospitalization varied from 8% to 98%. Initial admission to a hospital without EEG capability was associated with 22% increased likelihood of interhospital transfer (adjusted RR 1.22, [95% CI, 1.09-1.37]; p < 0.01). Among those hospitalized at an EEG-capable hospital, patients admitted to hospitals in the lowest quintile of EEG volume were more than 2 times more likely to undergo interhospital transfer (adjusted RR 2.22, [95% CI 1.65-2.93]; p < 0.001).

Discussion: A minority of hospitals are EEG capable yet care for most patients with SE. Inpatient EEG use, however, varies widely among EEG-capable hospitals, and lack of inpatient EEG access is associated with interhospital transfer. Given the high incidence and cost of SE, there is a need to better understand the importance and use of EEG in this patient population to further organize inpatient epilepsy systems of care to optimize outcomes.

Grants and funding

K23 NS116128/NS/NINDS NIH HHS/United States