A recurrent pleuropneumonia revealing Erdheim-Chester Disease

Yousra Kherabi; Thibaud Chazal; Jean-François Emile; Wassim Allaham; Elise Mallart; Victoire de Lastours; Julien Haroche; Yann Nguyen

doi:10.1016/j.rmcr.2023.101843

A recurrent pleuropneumonia revealing Erdheim-Chester Disease

Respir Med Case Rep. 2023 Apr 7:43:101843. doi: 10.1016/j.rmcr.2023.101843. eCollection 2023.

Authors

Yousra Kherabi¹, Thibaud Chazal², Jean-François Emile³, Wassim Allaham⁴, Elise Mallart¹, Victoire de Lastours^{1

5}, Julien Haroche², Yann Nguyen¹

Affiliations

¹ Service de Médecine Interne, AP-HP.Nord, Hôpital Beaujon, Université Paris Cité, Clichy, France.
² Service de Médecine Interne 2, Institut E3M, Inserm UMRS, Centre D'Immunologie et des Maladies Infectieuses (CIMI-Paris), Assistance Publique-Hôpitaux de Paris (APHP), Groupement Hospitalier Pitié-Salpêtrière, Sorbonne Université, Paris, France.
³ Service de Pathologie, Hôpital Ambroise-Paré, Boulogne, France.
⁴ Service de Radiologie, AP-HP.Nord, Hôpital Beaujon, Université Paris Cité, Clichy, France.
⁵ IAME Research Group, UMR-1137, Université de Paris, INSERM, Paris, France.

Abstract

Erdheim-Chester disease (ECD) is a rare form of L group histiocytosis, accounting for up to 1500 cases to date worldwide, which mainly affects men between their 5th and 7th decade of life. The most frequent manifestations are bone involvement, perirenal infiltration with an evocating appearance of "hairy kidneys", and a "coated aorta" aspect. Lung involvement in ECD is less common and includes pleural infiltration and interstitial lung disease. Herein, we report the case of a 76-year-old woman with recurrent pleuropneumonia revealing ECD.

Keywords: Erdheim-Chester; Histiocytosis; Pleuropneumonia.

Publication types

Case Reports