Microbiota transplant to control inflammation in a patient with NLRC4 gain-of-function-induced disease

Affiliations

• ¹ Division of Rheumatology, ERN RITA Center, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy.
• ² Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy.
• ³ Laboratory of Immuno-Rheumatology, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy.
• ⁴ Digestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy.
• ⁵ Centre for Paediatric Rheumatology and Autoinflammatory Diseases, ERN RITA Centre, Department of Paediatrics and Inherited Metabolic Disorders, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
• ⁶ Division of Rheumatology, ERN RITA Center, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy; Laboratory of Immuno-Rheumatology, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy. Electronic address: fabrizio.debenedetti@opbg.net.
• ⁷ Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy; Department of Diagnostic and Laboratory Medicine, Unit of Microbiology and Diagnostic Immunology, Unit of Microbiomics and Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Roma, Italy.