The Competition of Yin and Yang: Exploring the Role of Wild-Type and Mutant p53 in Tumor Progression

Biomedicines. 2023 Apr 17;11(4):1192. doi: 10.3390/biomedicines11041192.

Bi-He Cai¹, Yu-Te Sung², Chia-Chi Chen^{1

3

4

5}, Jei-Fu Shaw⁶, I-Lun Hsin⁷

¹ School of Medicine, I-Shou University, Kaohsiung City 82445, Taiwan.
² Department of Plastic Surgery, E-Da Hospital, I-Shou University, Kaohsiung City 82445, Taiwan.
³ Department of Physical Therapy, I-Shou University, Kaohsiung City 82445, Taiwan.
⁴ School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung City 82445, Taiwan.
⁵ Department of Pathology, E-Da Hospital, I-Shou University, Kaohsiung City 82445, Taiwan.
⁶ Department of Biological Science and Technology, I-Shou University, Kaohsiung City 82445, Taiwan.
⁷ Institute of Medicine, Chung Shan Medical University, Taichung City 40201, Taiwan.

Abstract

The protein p53 is a well-known tumor suppressor that plays a crucial role in preventing cancer development [...].