Bilateral post-LASIK exacerbation of granular corneal dystrophy with epithelial ingrowth

BMJ Case Rep. 2023 Jun 14;16(6):e254328. doi: 10.1136/bcr-2022-254328.

Abstract

A male patient in his 30s, with a history of bilateral microkeratome-assisted myopic laser-assisted in situ keratomileusis (LASIK) 8 years ago at another centre, presented to us with gradually progressive diminution of vision and glare in both eyes for the last 4 years. On presentation, uncorrected distance visual acuity (UDVA) was 6/24 and 6/15 in the right eye and left eye, respectively, with normal intraocular pressures. Slit-lamp examination and anterior segment optical coherence tomography revealed well-defined white deposits, limited to an area within the LASIK flap. The deposits were confluent, at the level of the LASIK flap interface, and few discrete opacities were present in the posterior stroma. His father also had a similar clinical picture in both eyes. A diagnosis of both eyes post-LASIK exacerbation of granular corneal dystrophy with epithelial ingrowth was made. He underwent right eye femtosecond laser-assisted sutureless superficial anterior lamellar keratoplasty. At 6-month follow-up, UDVA improved to 6/12 with graft clarity of 4+ and coexistent grade 1 epithelial ingrowth.

Keywords: Anterior chamber; Ophthalmology.

Publication types

  • Case Reports

MeSH terms

  • Corneal Dystrophies, Hereditary* / surgery
  • Eye
  • Humans
  • Keratomileusis, Laser In Situ* / adverse effects
  • Male
  • Myopia*
  • Slit Lamp Microscopy