Non-linear pharmacokinetics of 5-fluorouracil as described by in vivo behaviour of 5,6 dihydro-5-fluorouracil

Biochem Pharmacol. 1986 Aug 1;35(15):2461-5. doi: 10.1016/0006-2952(86)90041-9.

Authors

E A de Bruijn, L Remeyer, U R Tjaden, C Erkelens, L M de Brauw, C J van de Velde

PMID: 3741455
DOI: 10.1016/0006-2952(86)90041-9

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Dose-Response Relationship, Drug
Female
Fluorouracil / analogs & derivatives*
Fluorouracil / metabolism*
Half-Life
Kinetics
Rats

Substances

5-fluorodihydrouracil
Fluorouracil