SMART Syndrome: Case Report and Review of the Literature

Christophe Dossin; Dario Di Perri; Nicolas Whenham; Anna Paola Bocchio; Idil Gunes Tatar

doi:10.5334/jbsr.3198

SMART Syndrome: Case Report and Review of the Literature

J Belg Soc Radiol. 2023 Jul 6;107(1):49. doi: 10.5334/jbsr.3198. eCollection 2023.

Authors

Christophe Dossin¹, Dario Di Perri², Nicolas Whenham³, Anna Paola Bocchio¹, Idil Gunes Tatar¹

Affiliations

¹ Cliniques universitaires Saint Luc, Department of radiology, BE.
² Cliniques universitaires Saint Luc, Department of radiotherapy, BE.
³ Cliniques universitaires Saint Luc, Department of radiation oncology, BE.

Abstract

Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare condition characterized by stroke-like deficits, seizures, and headache that can occur years after radiation therapy (RT) to the brain. RT is a cornerstone in the treatment of primary brain tumours and is indicated in more than 90% of patients. It is therefore essential to be aware of this entity to prevent misdiagnosis leading to inappropriate treatment. In this article, typical imaging findings of this condition are presented through a case report and review of the literature.

Keywords: Migraine; Radiation; SMART; Stroke-like.