Sex- and timing-specific effects of fasting and caloric restriction

Sebastian J Hofer; Frank Madeo

doi:10.1016/j.cmet.2023.06.001

Sex- and timing-specific effects of fasting and caloric restriction

Cell Metab. 2023 Jul 11;35(7):1091-1093. doi: 10.1016/j.cmet.2023.06.001.

Authors

Sebastian J Hofer¹, Frank Madeo²

Affiliations

¹ Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria; Field of Excellence BioHealth, University of Graz, Graz, Austria; BioTechMed Graz, Graz, Austria.
² Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria; Field of Excellence BioHealth, University of Graz, Graz, Austria; BioTechMed Graz, Graz, Austria. Electronic address: frank.madeo@uni-graz.at.

PMID: 37437541
DOI: 10.1016/j.cmet.2023.06.001

Abstract

Optimizing food quantity and fasting time may improve health and lifespan. We summarize emerging knowledge on sex, age, and circadian timing as important determinants for the efficacy of dietary interventions and highlight results from Duregon et al. pointing to a favorable combination of caloric restriction (CR) and fasting in aged female mice.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Caloric Restriction*
Fasting*
Female
Longevity
Mice