Hydroxychloroquine-induced repetitive atypical pustular drug eruptions in the same patient separated by 12 years

Jeffrey Chen; Lauryn M Falcone; Arivarasan D Karunamurthy; Jonhan Ho; Joseph C English 3rd

doi:10.1002/ccr3.7677

Hydroxychloroquine-induced repetitive atypical pustular drug eruptions in the same patient separated by 12 years

Clin Case Rep. 2023 Jul 21;11(7):e7677. doi: 10.1002/ccr3.7677. eCollection 2023 Jul.

Authors

Jeffrey Chen¹, Lauryn M Falcone², Arivarasan D Karunamurthy³, Jonhan Ho³, Joseph C English 3rd²

Affiliations

¹ University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
² Department of Dermatology University of Pittsburgh Pittsburgh Pennsylvania USA.
³ Dermatopathology Section Unviversity of Pittsburgh Pittsburgh Pennsylvania USA.

Abstract

Hydroxychloroquine (HCQ) has been reported to cause pustular drug eruptions such as acute generalized exanthematous pustulosis (AGEP) and putular psoriasis (PP). Clinical differentitation of these entities is often difficult. This case emphasizes characteritics of AGEP and PP as well as the need for clinicans to proactively follow-up these patients to monitor for the more aggressive outcome of PP.

Keywords: acute generalized exanthematous pustulosis; drug eruption; hydroxychloroquine; pustular psoriasis; pustulosis.

Publication types

Case Reports