Parenteral Nutrition in the Neonatal Intensive Care Unit: Intravenous Lipid Emulsions

Abstract

Intravenous lipid emulsions (ILEs) are a source of nonprotein calories and fatty acids and help promote growth in preterm infants and infants with intestinal failure. An ILE dose and oil source determines its fatty acid, phytosterol, and vitamin E delivery. These factors play a role in the infant's risk for essential fatty acid deficiency and cholestasis, and help modulate inflammation, immunity, and organ development. This article reviews different ILEs and their constituents and their relationship with neonatal health.

Keywords: Fatty acids; Intestinal failure–associated liver disease; Lipids; Neonates; Parenteral nutrition; Premature.