Utility of late gadolinium enhancement on magnetic resonance imaging in hypertrophic cardiomyopathy patients in an Indian cohort

Harikrishnan Gangadharakaimal; Nitin Kumar Parashar; Mukund A Prabhu; Ayyappan Anoop; Narayanan Namboodiri

doi:10.1016/j.ihj.2023.08.001

Utility of late gadolinium enhancement on magnetic resonance imaging in hypertrophic cardiomyopathy patients in an Indian cohort

Indian Heart J. 2023 Sep-Oct;75(5):383-385. doi: 10.1016/j.ihj.2023.08.001. Epub 2023 Aug 9.

Authors

Harikrishnan Gangadharakaimal¹, Nitin Kumar Parashar², Mukund A Prabhu³, Ayyappan Anoop⁴, Narayanan Namboodiri⁵

Affiliations

¹ Department of Cardiology Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India, 695011. Electronic address: harigkaimal@gmail.com.
² Department of Cardiology Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India, 695011. Electronic address: nitinparashar46@gmail.com.
³ Department of Cardiology Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India, 695011. Electronic address: mukundaprabhu@gmail.com.
⁴ Department of Cardiology Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India, 695011. Electronic address: anoop.a@sctimst.ac.in.
⁵ Department of Cardiology Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India, 695011. Electronic address: kknnamboodiri@gmail.com.

Abstract

This prospective observational study sought to correlate segmental late gadolinium enhancement (LGE) seen in cardiac magnetic resonance imaging with occurrence of ventricular arrhythmias (VAs) in patients with hypertrophic cardiomyopathy. LGE was assessed in a 17-segmental model of heart. Of 57 patients, VAs were present in 26.3% of patients and 10.5% had sustained ventricular tachycardia. LGE was present in 43.9% of patients. Presence of LGE in 4 or more segments was associated with VAs with a sensitivity of 73% and specificity of 76% with area under curve of 0.733 in C-statistics.

Keywords: Cardiac magnetic resonance imaging; Hypertrophic cardiomyopathy; Late gadolinium enhancement.