1 Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 613A Stellar Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA.
2 Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
3 Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, 213 Blockley Hall, 423 Guardian Drive, Philadelphia, PA, 19104, USA.
4 Department of Information Theory and Data Science, School of Mathematical Sciences and LPMC, Nankai University, Tianjin, China.
5 School of Statistics and Data Science, Key Laboratory for Medical Data Analysis and Statistical Research of Tianjin, Nankai University, Tianjin, China.
6 Department of Statistics and Data Science, Carnegie Mellon University, Pittsburgh, PA, USA.
7 Graduate Group in Genomics and Computational Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
8 Heinz College of Public Policy and Information Systems, Carnegie Mellon University, Pittsburgh, PA, USA.
9 Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA, USA.
10 Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, 213 Blockley Hall, 423 Guardian Drive, Philadelphia, PA, 19104, USA. mingyao@pennmedicine.upenn.edu.
11 Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 613A Stellar Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA. edward.lee@pennmedicine.upenn.edu.
12 Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. edward.lee@pennmedicine.upenn.edu.