Seroprevalence of herpes simplex virus type 1 and type 2 among the migrant workers in Qatar

Virol J. 2023 Aug 22;20(1):188. doi: 10.1186/s12985-023-02157-1.

Abstract

Background: Limited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual workers (CMWs) in Qatar who constitute 60% of Qatar's population.

Methods: A national population-based cross-sectional seroprevalence survey was conducted on the CMW population, all men, between July 26 and September 9, 2020. 2,612 sera were tested for anti-HSV-1 IgG antibodies using HerpeSelect 1 ELISA IgG kits and for anti-HSV-2 IgG antibodies using HerpeSelect 2 ELISA IgG kits (Focus Diagnostics, USA). Univariable and multivariable logistic regression analyses were conducted to identify associations with HSV-1 and HSV-2 infections.

Results: Serological testing identified 2,171 sera as positive, 403 as negative, and 38 as equivocal for HSV-1 antibodies, and 300 sera as positive, 2,250 as negative, and 62 as equivocal for HSV-2 antibodies. HSV-1 and HSV-2 seroprevalences among CMWs were estimated at 84.2% (95% CI 82.8-85.6%) and 11.4% (95% CI 10.1-12.6%), respectively. HSV-1 infection was associated with nationality, educational attainment, and occupation. HSV-2 infection was associated with age, nationality, and educational attainment.

Conclusions: Over 80% of CMWs are infected with HSV-1 and over 10% are infected with HSV-2. The findings highlight the need for sexual health programs to tackle sexually transmitted infections among the CMW population.

Keywords: Cross sectional study; Genital herpes; Genital ulcer disease; HSV-1; HSV-2; Migrants; Prevalence; Qatar; Survey.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral
  • Cross-Sectional Studies
  • Herpes Simplex* / epidemiology
  • Herpesvirus 1, Human*
  • Herpesvirus 2, Human
  • Humans
  • Immunoglobulin G
  • Male
  • Qatar / epidemiology
  • Seroepidemiologic Studies
  • Transients and Migrants*

Substances

  • Antibodies, Viral
  • Immunoglobulin G