Epidemiology of Haemophilus influenzae in children on Lombok Island, Indonesia

Nina Dwi Putri; Korrie Salsabila; Ari Prayitno; Shindy Claudya Aprianti; Wisiva Tofriska Paramaiswari; Made Ananda Krisna; Dodi Safari

doi:10.1099/acmi.0.000609.v4

Epidemiology of Haemophilus influenzae in children on Lombok Island, Indonesia

Access Microbiol. 2023 Aug 2;5(8):acmi000609.v4. doi: 10.1099/acmi.0.000609.v4. eCollection 2023.

Authors

Nina Dwi Putri¹, Korrie Salsabila², Ari Prayitno¹, Shindy Claudya Aprianti¹, Wisiva Tofriska Paramaiswari², Made Ananda Krisna^{2

3}, Dodi Safari²

Affiliations

¹ Department of Child Health, Dr Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
² Eijkman Research Centre for Molecular Biology, National Research and Innovation Agency, Cibinong, West Java, Indonesia.
³ Present address: Biology Department and Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

Abstract

The Haemophilus influenzae serotype b (Hib) conjugate vaccine routine immunization programme has been implemented for almost a decade; however, there is limited surveillance of H. influenzae carriage rates in the Indonesian population. H. influenzae was isolated from nasopharyngeal (NP) swab specimens of healthy children on Lombok Island, West Nusa Tenggara Province, Indonesia from 2018 to 2019. Serotyping was performed using quantitative polymerase chain reaction. We identified H. influenzae in 40 of the 96 (41.6 %) NP swab specimens. We identified 39 non-typeable H. influenzae (NTHi) isolates and 1 Hib isolate.

Keywords: Haemophilus influenzae; Haemophilus influenzae serotype b; Lombok Island, Indonesia; non-typeable H. influenzae.