The acidic stretch and the C-terminal nuclear export signal motif of NPM1 mutant: are they druggable in AML?

Leukemia. 2023 Nov;37(11):2173-2175. doi: 10.1038/s41375-023-02037-1. Epub 2023 Sep 22.
No abstract available

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Leukemia, Myeloid, Acute* / drug therapy
  • Leukemia, Myeloid, Acute* / genetics
  • Mutation
  • Nuclear Export Signals*
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism
  • Nucleophosmin

Substances

  • Nuclear Export Signals
  • Nuclear Proteins
  • Nucleophosmin
  • NPM1 protein, human