Considerations for intensity modulated total body or total marrow and lymphoid irradiation

David Parsons; Tze Yee Lim; Jose R Teruel; Paulina Galavis; Stefano Agostinelli; Jieming Liang; Pietro Mancosu; Amanda Cherpak; Dennis N Stanley; Kang-Hyun Ahn; Bingqi Guo; Yesenia Gonzalez; Jay Burmeister; Jeffrey Y C Wong; Xuejun Gu; Grace Gwe-Ya Kim

doi:10.1016/j.ctro.2023.100674

Considerations for intensity modulated total body or total marrow and lymphoid irradiation

Clin Transl Radiat Oncol. 2023 Sep 9:43:100674. doi: 10.1016/j.ctro.2023.100674. eCollection 2023 Nov.

Authors

Affiliations

¹ Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
² Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
³ Department of Radiation Oncology, New York University Langone Health, New York, NY, USA.
⁴ IRCCS Ospedale Policlinico San Martino, Genova, Italy.
⁵ Department of Radiation Oncology, City of Hope National Medical Center City of Hope National Medical Center, Duarte, CA, USA.
⁶ IRCCS Humanitas Research Hospital, Medical Physics Unit, Rozzano, Milan, Italy.
⁷ Department of Radiation Oncology and Department of Medical Physics, Nova Scotia Health, Halifax, Nova Scotia, Canada.
⁸ Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
⁹ Department of Radiation Oncology, University of Illinois, Chicago, IL and Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
¹⁰ Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, OH, USA.
¹¹ Department of Oncology, Wayne State University School of Medicine, Karmanos Cancer Center, Detroit, MI, USA.
¹² Department of Radiation Oncology, Stanford University, Palo Alto, CA, USA.
¹³ Radiation Medicine and Applied Science, University of California San Diego, La Jolla, CA, USA.

Abstract

We compiled a sampling of the treatment techniques of intensity-modulated total body irradiation, total marrow irradiation and total marrow and lymphoid irradiation utilized by several centers across North America and Europe. This manuscript does not serve as a consensus guideline, but rather is meant to serve as a convenient reference for centers that are considering starting an intensity-modulated program.

Keywords: Intensity modulation; Total body irradiation; Total marrow irradiation.