Salt-Intake-Related Behavior Varies between Sexes and Is Strongly Associated with Daily Salt Consumption in Obese Patients at High Risk for MASLD

Nutrients. 2023 Sep 12;15(18):3942. doi: 10.3390/nu15183942.

Abstract

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) imposes a significant burden on Westernized regions. The Western diet, high in salt intake, significantly contributes to disease development. However, there are a lack of data on salt literacy and salt intake among MASLD patients in Germany. Our study aims to analyze daily salt intake and salt-intake-related behavior in MASLD patients.

Methods: 234 MASLD patients were prospectively included. Daily salt intake and salt-intake-related behavior were assessed via a food frequency questionnaire (FFQ-DEGS) and a salt questionnaire (SINU). Statistical analyses were performed using SPSS.

Results: Mean daily salt intake was higher in men than in women (7.3 ± 5 g/d vs. 5.3 ± 4 g/d; p < 0.001). There was significant agreement between increased daily salt intake (>6 g/d) and the behavioral salt index (SI) (p < 0.001). Men exhibited higher SI scores compared to women, indicating lower awareness of salt in everyday life. Multivariate analysis identified specific salt-intake-related behaviors impacting daily salt consumption.

Conclusions: Our study reveals a strong link between daily salt intake and salt-intake-related behavior, highlighting sex-specific differences in an MASLD cohort. To enhance patient care in high-cardiovascular-risk populations, specific behavioral approaches may be considered, including salt awareness, to improve adherence to lifestyle changes, particularly in male patients.

Keywords: MASLD; salt consumption; salt-intake-related behavior; steatotic liver disease.

MeSH terms

  • Fatty Liver*
  • Female
  • Humans
  • Male
  • Metabolic Diseases*
  • Obesity
  • Sexual Behavior
  • Sodium Chloride
  • Sodium Chloride, Dietary / adverse effects

Substances

  • Sodium Chloride, Dietary
  • Sodium Chloride

Grants and funding

B.H. received a scholarship by the Graduate School of Life Sciences of the University of Würzburg.