Incidence of deep vein thrombosis and symptomatic pulmonary embolism in Taiwanese patients with pelvic and/or acetabular fractures: a retrospective study

Sci Rep. 2023 Sep 28;13(1):16352. doi: 10.1038/s41598-023-43449-4.

Abstract

Venous thromboembolism (VTE) is common in patients with trauma, and thromboprophylaxis has been advocated. However, conflicting results regarding VTE rates in the Asian population following orthopaedic procedures have been presented. We aimed to investigate the VTE incidence in Taiwanese patients with pelvic and/or acetabular fractures and identify the associated risk factors. We included 402 patients who underwent surgery for pelvic and/or acetabular fractures. All patients received mechanical thromboprophylaxis with graduated compression stockings. Duplex scanning was performed postoperatively or during follow-up when signs or symptoms of deep vein thrombosis (DVT) developed. Variables with a significance level of ≤ 0.1 in the univariate analyses were introduced into the multivariate logistic regression analysis to identify DVT risk factors. The overall DVT and symptomatic pulmonary embolism (PE) rate was 3.48% (14/402 patients). Among patients with DVT, 46.1% were asymptomatic. Patients with VTE were significantly older than those without. Multivariate logistic regression analysis revealed that age was a VTE risk factor. The incidence of DVT and symptomatic PE in our cohort was low. Advanced age was a risk factor for VTE. These findings could help clinicians develop appropriate prevention and treatment strategies for VTE in Taiwanese patients with pelvic and/or acetabular fractures.

MeSH terms

  • Anticoagulants / therapeutic use
  • Hip Fractures* / complications
  • Humans
  • Incidence
  • Postoperative Complications / prevention & control
  • Pulmonary Embolism* / epidemiology
  • Pulmonary Embolism* / etiology
  • Pulmonary Embolism* / prevention & control
  • Retrospective Studies
  • Risk Factors
  • Spinal Fractures* / complications
  • Venous Thromboembolism* / epidemiology
  • Venous Thrombosis* / drug therapy
  • Venous Thrombosis* / epidemiology
  • Venous Thrombosis* / etiology

Substances

  • Anticoagulants