Prevalence and risk factors of subsyndromal delirium among postoperative patients: A systematic review and meta-analysis

J Adv Nurs. 2024 Mar;80(3):924-934. doi: 10.1111/jan.15871. Epub 2023 Oct 3.

Abstract

Aim: The aim of this study is to determine the prevalence and risk factors for subsyndromal delirium in the postoperative patient.

Design: A systematic review and meta-analysis.

Methods: The Review Manager 5.3 statistics platform and the Newcastle-Ottawa Scale were used for quality evaluation.

Data sources: The following databases were searched: PubMed, Web of Science, EMBASE, The Cochrane Library, Scopus and EBSCO from January 2000 to December 2021. Additional sources were found by looking at relevant articles' citations.

Results: A total of 1744 titles were originally identified, and five studies including 962 patients were included in the systematic review, with a pooled prevalence of postoperative subsyndromal delirium (PSSD) of 30% (95% CI: 0.28-0.32). Significant risk variables for PSSD were older age, low levels of education (≤9 years), cognitive impairment, higher comorbidity score, and the duration of operation.

Conclusion: PSSD is prevalent and is associated with a variety of risk factors as well as low academic performance.

Impact: Identification and clinical management of patients with PSSD should be improved. Future research on PSSD risk factors should look at a wider range of intraoperative and postoperative risk factors that can be changed.

Patient and public contribution: No Patient or Public Contribution.

Keywords: Subsyndromal delirium; meta-analysis; nurse; nursing; postoperative care; prevalence; risk factors; surgery.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Delirium* / epidemiology
  • Delirium* / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications* / epidemiology
  • Prevalence
  • Risk Factors