[Applications of single-cell analysis in blood research]

Rinsho Ketsueki. 2023;64(9):1047-1052. doi: 10.11406/rinketsu.64.1047.
[Article in Japanese]

Abstract

Single-cell analysis encompasses analyses at the single-cell level. Specifically, DNA sequences, RNA and protein expression levels, and epigenome modifications are currently analyzed at the single-cell level. In recent years, single-cell sequencing technologies have been incorporated into numerous blood studies. This paper introduces an overview of single-cell technologies and further explains achievements in blood research using single-cell analysis.

Keywords: Heterogeneity; Single-cell sequencing; Spatial transcriptomics.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Gene Expression Profiling
  • Humans
  • Sequence Analysis, DNA
  • Single-Cell Analysis*
  • Technology*
  • Transcriptome