Pooling method for screening large numbers of Escherichia coli for production of heat-stable enterotoxin, and its application in field studies

J Clin Microbiol. 1979 Apr;9(4):541-3. doi: 10.1128/jcm.9.4.541-543.1979.

Abstract

A modified suckling mouse assay was developed for use in field studies whereby five E. coli isolates could be tested as a pool for heat-stable enterotoxin.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Animals, Newborn
  • Biological Assay / methods*
  • Body Weight
  • Diarrhea / etiology*
  • Enterotoxins / biosynthesis*
  • Enterotoxins / pharmacology
  • Escherichia coli / metabolism*
  • Hot Temperature
  • Humans
  • Intestines / drug effects
  • Mice
  • Organ Size

Substances

  • Enterotoxins