Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia

Hui-Ling Qu; Xiao-Yu Sun; Ying-Jie Dai

doi:10.3389/fneur.2023.1216328

Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia

Front Neurol. 2023 Oct 24:14:1216328. doi: 10.3389/fneur.2023.1216328. eCollection 2023.

Authors

Hui-Ling Qu¹, Xiao-Yu Sun¹, Ying-Jie Dai¹

Affiliation

¹ Department of Neurology, The General Hospital of Northern Theater Command, Shenyang, China.

Abstract

Central pontine myelinolysis (CPM) is a heterogeneous nervous system disease of pontine demyelination, usually caused by rapid correction of hyponatremia. In the present study, we report a unique case of a 46-year-old man with a hyperglycemic state complicated with CPM. MRI demonstrated a high signal on T2 and symmetric restricted diffusion in the pontine. In conclusion, the clinical case described confirmed that the hyperosmolar state inherent in hyperglycemia was a likely cause of CPM.

Keywords: blood glucose; central pontine myelinolysis; hyperosmolar; hyponatremia; osmotic demyelination syndrome.

Publication types

Case Reports