Anaerobiosis, a neglected factor in phage-bacteria interactions

Appl Environ Microbiol. 2023 Dec 21;89(12):e0149123. doi: 10.1128/aem.01491-23. Epub 2023 Nov 15.

Abstract

Many parameters affect phage-bacteria interaction. Some of these parameters depend on the environment in which the bacteria are present. Anaerobiosis effect on phage infection in facultative anaerobic bacteria has not yet been studied. The absence of oxygen triggers metabolic changes in facultative bacteria and this affects phage infection and viral life cycle. Understanding how an anaerobic environment can alter the behavior of phages during infection is relevant for the phage therapy success.

Keywords: Salmonella; anaerobiosis; bacteriophages; molecular biology; transcriptomic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anaerobiosis
  • Bacteria
  • Bacteriophages*