Caregivers' burden and deep brain stimulation for Parkinson disease: A systematic review of qualitative studies

Eur J Neurol. 2024 Mar;31(3):e16149. doi: 10.1111/ene.16149. Epub 2023 Nov 17.

Abstract

Background and purpose: The impact of subthalamic nucleus deep brain stimulation (STN-DBS) on caregivers' burden is understudied. We perform a systematic review and meta-synthesis aggregating qualitative studies involving partners of people with Parkinson disease (PwP) to explore their experiences and unmet needs.

Methods: A systematic review for retrieving qualitative studies included six databases: MEDLINE, Embase, CINAHL, Cochrane, PsycInfo, and Scopus. Inclusion criteria were as follows: (i) studies on the experience of caregivers of PwP in the context of STN-DBS, (ii) English peer-reviewed articles, and (iii) qualitative or mixed methods studies reporting caregivers' quotations. After the appraisal of included studies, we performed meta-synthesis of qualitative findings. Descriptive themes and conceptual elements related to PwP partners' experiences and unmet needs were generated.

Results: A total of 1108 articles were screened, and nine articles were included. Three categories were identified: (i) dealing with Parkinson disease (PD) every day (the starting situation characterized by the impact of PD on ordinary life; the limitations to partners' socialization; partners' efforts in stepping aside for love and care activities), (ii) facing life changes with STN-DBS (the feeling of being unprepared for changes; the fear and concern due to loved ones' behavioral changes; struggling to find an explanation for those changes), and (iii) rebuilding the role of caregiver and partner after STN-DBS.

Conclusions: This meta-synthesis elucidates concerns, challenges, and unmet needs of partners of PwP who underwent STN-DBS. It is important to provide them with information, education, and adequate support to face these challenges. Professionals need to involve partners in the care and decision process, because STN-DBS-related outcomes do not depend solely on the well-being of PwP but also on the well-being of individuals surrounding them.

Keywords: Parkinson's disease; burden; care partner; caregiver; deep brain stimulation; meta-synthesis; qualitative research.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Caregiver Burden / psychology
  • Caregivers* / psychology
  • Cost of Illness
  • Deep Brain Stimulation*
  • Humans
  • Parkinson Disease* / psychology
  • Parkinson Disease* / therapy
  • Qualitative Research