Weekend and holiday admissions for decompensated heart failure and in-hospital mortality. A cumulative effect of "nonworking" days?

Rev Esp Cardiol (Engl Ed). 2024 Jun;77(6):440-447. doi: 10.1016/j.rec.2023.10.003. Epub 2023 Nov 15.
[Article in English, Spanish]

Abstract

Introduction and objectives: The aim of this study was to analyze whether nonelective admissions in patients with heart failure (HF) on nonworking days (NWD) are associated with higher in-hospital mortality.

Methods: We conducted a retrospective (2018-2019) observational study of episodes of nonelective admissions in patients aged 18 years and older discharged with a principal diagnosis of HF in acute general hospitals of the Spanish National Health System. NWD at admission were defined as Fridays after 14:00hours, Saturdays, Sundays, and national and regional holidays. In-hospital mortality was analyzed with logistic regression models. The length of NWD was considered as an independent continuous variable. Propensity score matching was used as a sensitivity analysis.

Results: We selected 235 281 episodes of nonelective HF admissions. When the NWD periods were included in the in-hospital mortality model, the increases in in-hospital mortality compared with weekday admission were as follows: 1 NWD day (OR, 1.11; 95%CI, 1.07-1.16); 2 days (OR, 1.13; 95%CI, 1.09-1.17); 3 (OR, 1.16; 95%CI, 1.05-1.27); and ≥4 days (OR, 1.20; 95%CI, 1.09-1.32). There was a statistically significant association between a linear increase in NWD and higher risk-adjusted in-hospital mortality (chi-square trend P=.0002). After propensity score matching, patients with HF admitted on NWD had higher in-hospital mortality than those admitted on weekdays (OR, 1.11; average treatment effect, 12.2% vs 11.1%; P<.001).

Conclusions: We found an association between admissions for decompensated HF on an NWD and higher in-hospital mortality. The excess mortality is likely not explained by differences in severity. In this study, the "weekend effect" tended to increase as the NWD period became longer.

Keywords: Calidad; Clinical management; Gestión clínica; Heart failure; Insuficiencia cardiaca; Quality; «Efecto fin de semana»; “Weekend effect”.

Publication types

  • Observational Study
  • Multicenter Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Heart Failure* / mortality
  • Heart Failure* / therapy
  • Holidays*
  • Hospital Mortality* / trends
  • Hospitalization / statistics & numerical data
  • Hospitalization / trends
  • Humans
  • Male
  • Middle Aged
  • Patient Admission / statistics & numerical data
  • Patient Admission / trends
  • Propensity Score
  • Retrospective Studies
  • Spain / epidemiology
  • Time Factors