Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance

Wolfgang von Scheidt; Bruno Reichart; Bruno Meiser; Moritz von Scheidt; Partho Sen; Florian Schwarz; Eva Harmel; Frank M Bengel; Andrea Dick; Peter Ueberfuhr; Hermann Reichenspurner; Elmar Jaeckel; Reinhard Schwinzer; Christian Hagl

doi:10.1007/s00392-023-02341-x

Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance

Clin Res Cardiol. 2024 May;113(5):661-671. doi: 10.1007/s00392-023-02341-x. Epub 2023 Nov 20.

Authors

Wolfgang von Scheidt^#^{1

2}, Bruno Reichart^#³, Bruno Meiser⁴, Moritz von Scheidt^{5

6}, Partho Sen^{5

6}, Florian Schwarz^{7

8}, Eva Harmel⁹, Frank M Bengel¹⁰, Andrea Dick¹¹, Peter Ueberfuhr³, Hermann Reichenspurner¹², Elmar Jaeckel¹³, Reinhard Schwinzer¹⁴, Christian Hagl^{3

6}

Affiliations

¹ I.Medizinische Klinik, University Hospital Augsburg, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany. w.scheidt@med1-klinikum-augsburg.de.
² Ludwig-Maximilians-University Munich, Munich, Germany. w.scheidt@med1-klinikum-augsburg.de.
³ Department of Cardiac Surgery, University Hospital Großhadern, Ludwig-Maximilians-University Munich, Munich, Germany.
⁴ Transplant Center, University Hospital Großhadern, Ludwig-Maximilians-University Munich, Munich, Germany.
⁵ Department of Cardiovascular Diseases, German Heart Center Munich, Technical University Munich, Munich, Germany.
⁶ DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
⁷ Ludwig-Maximilians-University Munich, Munich, Germany.
⁸ Department of Diagnostic and Interventional Radiology, University Hospital Augsburg, University of Augsburg, Augsburg, Germany.
⁹ I.Medizinische Klinik, University Hospital Augsburg, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany.
¹⁰ Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
¹¹ Laboratory for Immunogenetics and Molecular Diagnostics, University Hospital Großhadern, Ludwig-Maximilians-University Munich, Munich, Germany.
¹² Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
¹³ Ajmera Transplant Center, UHN, University of Toronto, Toronto, Canada.
¹⁴ Department of General-, Visceral- and Transplantation-Surgery, Hannover Medical School, Hannover, Germany.

^# Contributed equally.

Abstract

Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance.

Keywords: Cardiac allograft vasculopathy; Heart transplantation; Immunosuppression; Long-term survival; Myocardial function; Tolerance.

Publication types

Letter

MeSH terms

Graft Rejection
Graft Survival*
Heart Transplantation*
Humans

Grants and funding

DZHK-81X3600506/DZHK