Cytogenetics Is a Science, Not a Technique! Why Optical Genome Mapping Is So Important to Clinical Genetic Laboratories

Cancers (Basel). 2023 Nov 19;15(22):5470. doi: 10.3390/cancers15225470.

¹ Department of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
² Department of Human Genetics and Department of Internal Medicine, Research Institute for Medical Innovation, Radboud Expertise Center for Immunodeficiency and Autoinflammation and Radboud Center for Infectious Disease (RCI), Radboud University Medical Center, 6525 Nijmegen, The Netherlands.
³ Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.

Abstract

Karyotyping is a technique that has been used in clinical cytogenetic laboratories for more than 40 years [...].