Postpartum cryptococcosis in an HIV-negative patient

Infection. 2024 Apr;52(2):691-696. doi: 10.1007/s15010-023-02151-3. Epub 2023 Dec 19.

Abstract

Purpose and methods: We present an unusual case of an HIV-negative patient with postpartum pulmonary cryptococcosis and cryptococcemia.

Results: The diagnostic methods and treatment of cryptococcosis in a postpartum patient are presented in this case report. Due to anaphylaxis to liposomal amphotericin B, desensitisation to the drug was performed.

Conclusion: We would like to raise awareness about rare infections such as cryptococcosis in pregnancy and the postpartum period. In addition, we were able to document a successful desensitisation to liposomal amphotericin B.

Keywords: Cryptococcemia; Cryptococcosis; Desensitisation; Liposomal amphotericin B; Postpartum infection.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B*
  • Antifungal Agents / therapeutic use
  • Cryptococcosis* / diagnosis
  • Cryptococcosis* / drug therapy
  • Cryptococcus neoformans*
  • Female
  • HIV Infections* / drug therapy
  • Humans
  • Postpartum Period
  • Pregnancy

Substances

  • liposomal amphotericin B
  • Antifungal Agents
  • Amphotericin B